Accelerator Mass Spectrometry, or AMS, is a technique for measuring isotope ratios with very high selectively, sensitivity and precision. It was originally developed as a geophysical instrument to do carbon dating of artifacts. About two decades ago, the Lawrence Livermore National Laboratory developed it to do biomedical applications.
“We were kind of the pioneers in that front and it’s just kind of taken off from there. We’ve looked at low levels of environmental toxicants and now we’re getting into the human area so we can do actual real world human experiments using this type of technology.”
That’s medical scientist Mike Malfatti of the Livermore Lab. He’s been using a new biological AMS instrument to develop a test to predict how people will respond to chemotherapeutic drugs. Malfatti and this team have been working with colleagues at the University of California, Davis.
“It’s really opened up a lot of opportunities for us – almost a whole new field of study being able to actually do real in-human studies where previously those studies weren’t able to be done.”
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